Transient acantholytic dermatosis in a patient with prostate cancer

Transient acantholytic dermatosis (TAD) is a relatively common entity that has been also noted to occur in patients with cancer. Herein, we describe a case of transient acantholytic dermatosis occurring in a patient with a history of prostate cancer status post radiation, now being treated with combination therapy with pembrolizumab and carboplatin-pemetrexed for advanced lung adenocarcinoma. Our case emphasizes the importance of being cognizant of TAD and its associations, particularly in cancer patients

Signal Detection for QPSK Based Cognitive Radio Systems using Support Vector Machines

Cognitive radio based network enables opportunistic dynamic spectrum access by sensing, adopting and utilizing the unused portion of licensed spectrum bands. Cognitive radio is intelligent enough to adapt the communication parameters of the unused licensed spectrum. Spectrum sensing is one of the most important tasks of the cognitive radio cycle. In this paper, the auto-correlation function kernel based Support Vector Machine (SVM) classifier along with Welch's Periodogram detector is successfully implemented for the detection of four QPSK (Quadrature Phase Shift Keying) based signals propagating through an AWGN (Additive White Gaussian Noise) channel. It is shown that the combination of statistical signal processing and machine learning concepts improve the spectrum sensing process and spectrum sensing is possible even at low Signal to Noise Ratio (SNR) values up to -50 dB

Coloniality, just war & carceral injustice in Brazil

The Portuguese empire brought inescapable violence to the indigenous communities of Brazil and to those it enslaved. Throughout the centuries of colonial subjugation, driven by the Iberian monarchical traditions of hierarchy, militarism and moral crusade, ‘just war’ narratives were employed to legitimate the use of violent legal and extra-legal measures against enslaved peoples and others deemed unruly or rebellious and a threat to colonial order. Two centuries after independence, Brazil remains at war with its ‘internal enemies’. Its justice practices continue to be characterised by colonial rationalisations. This paper illustrates the contemporary coloniality inherent in the carceral system from the moment of detention pre-trial through sentencing and imprisonment

Chiral transition in a magnetic field and at finite baryon density

We consider the quark-meson model with two quark flavors in a constant external magnetic field $B$ at finite temperature $T$ and finite baryon chemical potential $\mu_B$. We calculate the full renormalized effective potential to one-loop order in perturbation theory. We study the system in the large-$N_c$ limit, where we treat the bosonic modes at tree level. It is shown that the system exhibits dynamical chiral symmetry breaking, i. e. that an arbitrarily weak magnetic field breaks chiral symmetry dynamically, in agreement with earlier calculations using the NJL model. We study the influence on the phase transition of the fermionic vacuum fluctuations. For strong magnetic fields, $|qB|\sim5m_{\pi}^2$ and in the chiral limit, the transition is first order in the entire $\mu_B-T$ plane if vacuum fluctuations are not included and second order if they are included. At the physical point, the transition is a crossover for $\mu_B=0$ with and without vacuum fluctuations.Comment: 11 pages. 5figs. V2: fixed a few typos and added refs. Submitted to PRD. V3: Added refs and substantial revision of tex

Secular Foundations of Liberal Multiculturalism

In pursuit of a just political order, Will Kymlicka has defended a liberal conception of multiculturalism. The persuasive appeal of his argument, like that of secular-liberalism more generally, is due to presenting liberalism as a neutral and universal political project. Utilizing Charles Taylor’s genealogy of ‘exclusive humanism’ in A Secular Age, this thesis attempts to re-read Kymlicka in order to make certain theological commitments in his work explicit. Here I argue that Kymlicka, in order to make his conception of multiculturalism plausible, relies on a theologically-thick and controversial humanism operating under secular conditions of belief. By committing himself to a particular conception of the human and specific conditions of belief, Kymlicka’s liberal multiculturalism is rendered provincially incoherent because it fails to treat in a neutral manner certain theological commitments

Endocrine and Cell Surface Receptor Signaling in Breast Carcinogenesis

Breast cancer is the most commonly diagnosed cancer and the leading cause of cancer-related death in female. To better understand the growth and progression as well as therapeutic management, breast cancers are grouped based on histopathological and molecular classification. A number of factors have been implicated in the development of breast cancer. Various cell surface as well as hormone receptor signaling play crucial role in breast cancer initiation and progression. This chapter briefly discusses few of the important receptor signaling pathways and the various strategies in practice as well as at different stages of development to target these pathways